On April 5, 2013, Clark, J. Stephen; Yang, Guang; Osnowski, Andrew P. published an article.Formula: C5H10O3 The title of the article was Synthesis of the C-1-C-17 Fragment of Amphidinolides C, C2, C3, and F. And the article contained the following:
The C1-C17 fragment, I, of amphidinolides C, C2, C3, and F has been constructed from a trans-2,5-disubstituted dihydrofuranone II prepared by diastereoselective rearrangement of a free or metal-bound oxonium ylide generated from a metal carbenoid (no data). The dihydrofuranone was converted into aldehyde III, which corresponds to the C1-C8 framework, and this was coupled to the C9-C17 unit IV by nucleophilic addition of a vinylic anion. The experimental process involved the reaction of (R)-Methyl 3-hydroxybutanoate(cas: 3976-69-0).Formula: C5H10O3
The Article related to amphidinolide c1 c17 fragment enantioselective synthesis, stereoselective aldol amphidinolide c1 c17 fragment enantioselective synthesis, regioselective hydrostannylation amphidinolide c1 c17 fragment enantioselective synthesis, tin lithium exchange amphidinolide c1 c17 fragment enantioselective synthesis and other aspects.Formula: C5H10O3
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