Nakamura, Kazuhito; Morita, Yukari; Suzuki, Toru; Sugiyama, Toru; Sugimori, Akira published the artcile< Radiation-induced reactions of pyridinecarboxylic esters in acidic alcoholic solutions. Substitution by alkyl and hydroxyalkyl groups and reduction of carboxylic esters to alcohol>, Application In Synthesis of 33402-75-4, the main research area is radiolysis pyridinecarboxylate alc; alkylation pyridinecarboxylate alc radiolysis; hydroxyalkylation pyridinecarboxylate alc radiolysis; reduction pyridinecarboxylate alc radiolysis.
The main reactions of pyridinecarboxylic esters induced by 60Co �rays in acidic alc. solutions are substitution on the pyridine ring by alkyl or hydroxyalkyl groups, derived from solvent alcs., and reduction of the carboxylate group to a hydroxymethyl group. Substitution is dominant in MeOH solutions and reduction is dominant in Me2CHOH solutions Carboxylic esters at the 2- and 4-positions are selectivity reduced to alcs. Alkylation results from the attack by H atoms and hydroxyalkyl radicals. Reduction of carboxylic esters to alcs. is effected by the hydroxyalkyl radicals derived from the radiolysis of alcs.
Bulletin of the Chemical Society of Japan published new progress about Radiochemical reduction. 33402-75-4 belongs to class esters-buliding-blocks, and the molecular formula is C8H9NO2, Application In Synthesis of 33402-75-4.
Referemce:
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