Zhang, Keke; Yang, Yihang; Zhuang, Jianfeng; Guo, Gengyin; Chao, Xin; Zhang, Zhen published the artcile< Intracranial dissemination of glioblastoma multiforme: a case report and literature review.>, Safety of (9Z,12Z)-Methyl octadeca-9,12-dienoate, the main research area is Glioblastoma; case report; intracranial dissemination; no-touch strategy; prognosis; temozolomide.
Intracranial dissemination is rare among patients with glioblastoma multiforme (GBM). Very few GBM patients develop symptoms from intracranial dissemination, as most do not surviving long enough for intracranial dissemination to become clinically evident. Herein, we report a case of GBM in a 39-year-old woman who underwent surgical resection, concomitant chemoradiotherapy, and seven courses of adjuvant chemotherapy with temozolomide. The patient then complained of an instable gait and hearing loss. Imaging studies demonstrated that although the primary intracranial tumors were well-controlled by treatment, contralateral cerebellopontine angle seeding dissemination was present. The patient died 3 months after the diagnosis of seeding dissemination. In light of a previous report and our current case, heightened awareness could promote surgical strategies that minimize the possibility of dissemination, including avoiding ventricular entry or a no-touch strategy.
The Journal of international medical research published new progress about 112-63-0. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Safety of (9Z,12Z)-Methyl octadeca-9,12-dienoate.
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