In 2019,Journal of Molecular Structure included an article by Tan, Hong-bo; Li, Hao; Xu, Jia; Song, Gui-ting; Meng, Jiang-ping. HPLC of Formula: 623-47-2. The article was titled 《Synthesis, NMR analysis and X-ray crystal structure of novel 1,5-dibenzyl-1,2,5,6-tetrahydro-1,5-diazocines》. The information in the text is summarized as follows:
Novel eight-membered 1,5-dibenzyl-1,2,5,6-tetrahydro-1,5-diazocines I [R = H, 4-Me, 4-F, 4-MeO, 2,4-di-F, 2,4-di-MeO] were prepared by a new three-component aza-annulation as one-pot method from paraformaldehyde, Et propiolate and benzylamine. Unique structure of products, an easy exptl. workup, the use of simple and available starting materials, and the high atom economy were the main advantages of this method. The target compound was isolated and unambiguously confirmed by NMR spectra (1D-NMR and 2D-NMR), high-resolution mass spectrometry and single-crystal X-ray diffraction anal. Furthermore, the products possessed N-benzyl-protected secondary amines and β-enamine esters, which could serve in further functionalizations to produce mol. diversity for use in medicinal and synthetic chem. In the experiment, the researchers used many compounds, for example, Ethyl propiolate(cas: 623-47-2HPLC of Formula: 623-47-2)
Ethyl propiolate(cas: 623-47-2) is a clear colorless to pale yellow liquid that is soluble in ethanol, ether and chloroform. It an important organic chemical raw material and pharmaceutical intermediate. Ethyl propargylate is obtained by oxidation of propargyl alcohol to propargylic acid followed by esterification.HPLC of Formula: 623-47-2
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics