Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 39149-80-9, name is tert-Butyl 2-bromopropanoate, This compound has unique chemical properties. The synthetic route is as follows., Recommanded Product: tert-Butyl 2-bromopropanoate
General procedure: A solution of NaHMDS (1.0 M in THF, 2.1 mL, 2.1 mmol) was added dropwise to the solution of 15 (R4 and R5 are methyl, 334 mg, 2.0 mmol) in THF (10 mL) at 78 C under argon. After 5 min, a solution of 16 (152 mg, 1.0 mmol) in THF (5 mL) was added dropwise. After another 5 min, the reaction was quenched with saturated ammonium chloride solution. The aqueous phase was extracted with EtOAc (3 20 mL). The combined organic layer was washed with saturated brine and dried over Na2SO4. The solvent was removed under reduced pressure
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 39149-80-9.
Reference:
Article; Li, Qing; Xiao, Fenfen; Wang, Yunxia; Hu, Xiangdong; Synthetic Communications; vol. 46; 12; (2016); p. 1062 – 1067;,
Ester – Wikipedia,
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