Fan, Yan-Ru; Wang, Bo-Jin; Jia, Deng-Guo; Yang, Xin-Bin; Huang, Yu published an article in 2021. The article was titled 《Synthesis, electrochemistry, DNA binding and in vitro cytotoxic activity of tripodal ferrocenyl bis-naphthalimide derivatives》, and you may find the article in Journal of Inorganic Biochemistry.Recommanded Product: tert-Butyl (5-aminopentyl)carbamate The information in the text is summarized as follows:
Tripodal ferrocenyl bis-naphthalimide derivatives were synthesized and characterized. All of the bis-naphthalimide derivatives exhibited good DNA binding ability which was confirmed by ethidium bromide (EB) displacement experiment and UV-visible absorption titration The binding mode of these compounds is a hybrid binding mode. The cytotoxicity of the synthesized compounds against 4 different human cancer cell lines (EC109, BGC823, SGC7901 and HEPG2) was evaluated by thiazolyl blue tetrazolium bromide (MTT) assay. All of the bis-naphthalimide derivatives exhibited better anticancer activity than the pos. control drug (amonafide), which was due to the promotion of reactive O species (ROS) level in test cancer cells by the reversible 1-electron redox process of ferrocenyl bis-naphthalimide derivatives Although there was no obvious relation between the binding constants and the chain length between ferrocenyl and naphthalimides, the structure cytotoxicity relation revealed that one compound was the best choice for the tested tripodal bis-naphthalimide derivatives In the experiment, the researchers used tert-Butyl (5-aminopentyl)carbamate(cas: 51644-96-3Recommanded Product: tert-Butyl (5-aminopentyl)carbamate)
Some of the reported applications of tert-Butyl (5-aminopentyl)carbamate(cas: 51644-96-3) include: synthesis of of a supermacrocycle that self-assemble to form organic nanotubes., preparation of water-soluble unsymmetrical sulforhodamine fluorophores from monobrominated sulfoxanthene dye, synthesis of functionalized porphyrins as biocompatible carrier system for photodynamic therapy (PDT).Recommanded Product: tert-Butyl (5-aminopentyl)carbamate
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