Liu, Hao-Nan; Cao, Hao-Qiang; Cheung, Chi Wai; Ma, Jun-An published the artcile< Cu-Mediated Expeditious Annulation of Alkyl 3-Aminoacrylates with Aryldiazonium Salts: Access to Alkyl N2-Aryl 1,2,3-Triazole-carboxylates for Druglike Molecular Synthesis>, Synthetic Route of 94-02-0, the main research area is aryldiazonium salt alkyl aminoacrylate preparation copper heterocyclization; alkyl aryltriazole carboxylate preparation.
A Cu-mediated annulation reaction of alkyl 3-aminoacrylates with aryldiazonium salts was described, both of which were readily available substrates. Furthermore, alkyl 2-aminoacrylates were also viable substrates. Diverse alkyl N2-aryl 1,2,3-triazole-carboxylates and their analogs was rapidly prepared under mild conditions. Especially, this protocol allowed one to access several druglike variants of carbonic anhydrase inhibitors and celecoxib.
Organic Letters published new progress about Amino esters Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 94-02-0 belongs to class esters-buliding-blocks, and the molecular formula is C11H12O3, Synthetic Route of 94-02-0.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics