In 2013,Angewandte Chemie, International Edition included an article by Lv, Hongbin; Cai, Yuan-Bo; Zhang, Jun-Long. Category: esters-buliding-blocks. The article was titled 《Copper-Catalyzed Hydrodefluorination of Fluoroarenes by Copper Hydride Intermediates》. The information in the text is summarized as follows:
We have reported the first example of copper-catalyzed hydrodefluorination of fluoroarenes using silanes as a hydrogen source. Copper exhibited high reactivity and regioselectivity toward a broad scope of fluoroarenes. Moreover, copper hydrides were observed during catalytic process and the unprecedented reactivity toward C-F bonds has been demonstrated. Furthermore, DFT calculations suggest a mechanism for nucleophilic attack on the C-F bonds by the copper hydride. This work presents valuable insights for further studies using copper catalysts for C-F bond functionalization. The experimental part of the paper was very detailed, including the reaction process of Ethyl 2,3,4,5,6-pentafluorobenzoate(cas: 4522-93-4Category: esters-buliding-blocks)
Ethyl 2,3,4,5,6-pentafluorobenzoate(cas: 4522-93-4) belongs to esters. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. Category: esters-buliding-blocks
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics