《Hydrosulfonylation of Alkenes with Sulfonyl Chlorides under Visible Light Activation》 was published in Angewandte Chemie, International Edition in 2020. These research results belong to Hell, Sandrine M.; Meyer, Claudio F.; Misale, Antonio; Sap, Jeroen B. I.; Christensen, Kirsten E.; Willis, Michael C.; Trabanco, Andres A.; Gouverneur, Veronique. Formula: C5H6O2 The article mentions the following:
Sulfonyl chlorides are inexpensive reactants extensively explored for functionalization, but never considered for radical hydrosulfonylation of alkenes. Herein, the authors report that tris(trimethylsilyl)silane is an ideal hydrogen atom donor enabling highly effective photoredox-catalyzed hydrosulfonylation of electron-deficient alkenes with sulfonyl chlorides. To increase the generality of this transformation, polarity-reversal catalysis (PRC) was successfully implemented for alkenes bearing alkyl substituents. This late-stage functionalization method tolerates a remarkably wide range of functional groups, is operationally simple, scalable, and allows access to building blocks which are important for medicinal chem. and drug discovery. In addition to this study using Ethyl propiolate, there are many other studies that have used Ethyl propiolate(cas: 623-47-2Formula: C5H6O2) was used in this study.
Ethyl propiolate(cas: 623-47-2) is a clear colorless to pale yellow liquid that is soluble in ethanol, ether and chloroform. It an important organic chemical raw material and pharmaceutical intermediate. Ethyl propargylate is obtained by oxidation of propargyl alcohol to propargylic acid followed by esterification.Formula: C5H6O2
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics