Category: esters-buliding-blocksIn 2021 ,《Controlled Ring-Opening Polymerization of Macrocyclic Monomers Based on the Quinone Methide Elimination Cascade Reaction》 was published in Macromolecules (Washington, DC, United States). The article was written by He, Yuxiang; Wu, Ying; Zhang, Minghui; Zhang, Yuanxing; Ding, Hao; Zhang, Ke. The article contains the following contents:
A controlled ring-opening polymerization (ROP) of macrocyclic monomers was developed based on the nucleophilic ring-opening mechanism for the first time. This novel ROP was designed to prepare backbone functional and sequence-defined polymers with controlled mol. weights and narrow dispersities (D < 1.1) by polymerizing the macrocycles with a quinone methide elimination-based self-immolative spacer as the ""ring-opening trigger"". This ROP was initiated by an efficient nucleophilic substitution of activated carbonate with a primary amine to ring open the macrocyclic monomers. The following spontaneous 1,6-elimination-decarboxylation cascade reaction disassembled the self-immolative spacer to regenerate the primary amine end group for subsequent polymer chain propagation. The versatility of this novel ROP was demonstrated by the formation of well-defined water-soluble, backbone-degradable, and sequence-defined polyurethanes and their block copolymers. The experimental process involved the reaction of N-Boc-1,6-Diaminohexane(cas: 51857-17-1Category: esters-buliding-blocks)
N-Boc-1,6-Diaminohexane(cas: 51857-17-1) is used to prepare 1,3-Bis[6-(Boc-amino)hexyl]urea by reacting with carbonyl dichloride in the presence of triethylamine. Further, it is used as a reagent for the introduction of a C6-spacer.Category: esters-buliding-blocks
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics