In 2019,Journal of the Brazilian Chemical Society included an article by Riatto, Valeria B.; Victor, Mauricio M.; Sousa, Jaqueline F.; Menegola, Carla. Reference of Diethyl 2-hydroxypentanedioate. The article was titled 《Biotechnological properties of sponges from Northeast Brazil: Cliona varians as a biocatalyst for enantioselective reduction of carbonyl compounds》. The information in the text is summarized as follows:
To research the potential ability of whole marine sponges to act as biocatalysts, this paper describes for the first time the employment of whole Cliona varians sponge in the stereoselective reduction of prochiral α-keto esters and isatin to the corresponding chiral alcs. The addition of D-fructose, D-glucose or sucrose remarkably increased the conversion ratios and stereoselectivities by this marine sponge. Furthermore, in the presence of D-glucose and D-maltose, the reduction of isatin by C. varians afforded the corresponding 3-hydroxyindolin-2-one with high conversions (85-90%) and good enantioselectivities (60-74%). These results showed that the marine sponge presents great potential to be used as biocatalyst for stereoselective reduction of carbonyl compounds After reading the article, we found that the author used Diethyl 2-hydroxypentanedioate(cas: 69134-53-8Reference of Diethyl 2-hydroxypentanedioate)
Diethyl 2-hydroxypentanedioate(cas: 69134-53-8) belongs to esters. Esters are more polar than ethers but less polar than alcohols. Reference of Diethyl 2-hydroxypentanedioate They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics