HPLC of Formula: 623-47-2In 2022 ,《Copper-catalyzed C-H/N-H annulation of enaminones and alkynyl esters for densely substituted pyrrole synthesis》 appeared in Chemical Communications (Cambridge, United Kingdom). The author of the article were Fu, Leiqing; Wan, Jie-Ping; Zhou, Liyun; Liu, Yunyun. The article conveys some information:
Herein, the copper-catalyzed annulation of enaminones R1C(O)CH=C(NH2)R2 (R1 = Me, Ph, naphthalen-2-yl, thiophen-2-yl, etc.; R2 = Me, Ph, n-Pr) with alkynyl esters HCCC(O)OR3 and R3C(O)OCCC(O)OR3 (R3 = Et, Me, t-Bu) for the facile synthesis of different pyrroles with 2,3,4,5-tetrasubstituted structures I and II has been developed. With Cu(OAc)2 as the only catalyst, the tunable synthesis of 2-vinyl I and 2,3-dicarboxyl-functionalized pyrroles II has been achieved by using terminal and internal alkynyl esters, resp. The synthesis of 2-vinyl pyrroles I represents the first example accessing 2-vinyl substituted pyrroles I via direct cascade reactions involving vinylation and pyrroles II ring formation. In addition to this study using Ethyl propiolate, there are many other studies that have used Ethyl propiolate(cas: 623-47-2HPLC of Formula: 623-47-2) was used in this study.
Ethyl propiolate(cas: 623-47-2) is a clear colorless to pale yellow liquid that is soluble in ethanol, ether and chloroform. It an important organic chemical raw material and pharmaceutical intermediate. Ethyl propargylate is obtained by oxidation of propargyl alcohol to propargylic acid followed by esterification.HPLC of Formula: 623-47-2
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics