《Introducing aldehyde functionality to proteins using ligand-directed affinity labeling》 was published in Chemical Communications (Cambridge, United Kingdom) in 2020. These research results belong to Song, Yinan; Xiong, Feng; Peng, Jianzhao; Fung, Yi Man Eva; Huang, Yiran; Li, Xiaoyu. Quality Control of N-Boc-1,6-Diaminohexane The article mentions the following:
Aldehyde is a versatile chem. handle for protein modification. Although many methods have been developed to label proteins with aldehyde, target-specific methods amenable to endogenous proteins are limited. Here, the authors report a simple affinity probe strategy to introduce aldehydes to native proteins. Notably, the probe contains a latent aldehyde functionality that is only exposed upon target binding, thereby enabling a one-pot labeling procedure. In addition to this study using N-Boc-1,6-Diaminohexane, there are many other studies that have used N-Boc-1,6-Diaminohexane(cas: 51857-17-1Quality Control of N-Boc-1,6-Diaminohexane) was used in this study.
N-Boc-1,6-Diaminohexane(cas: 51857-17-1) can be used as a linear hexyl spacer (C6-spacer) to synthesize biodegradable poly(disulfide amine)s for gene delivery, a multifunctional dendrimer for theranostics and so on.Quality Control of N-Boc-1,6-Diaminohexane
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