Weber, Edwin; Reutel, Christiane; Foces-Foces, Concepcion; Llamas-Saiz, Antonio L. published an article on January 31 ,1999. The article was titled 《Supramolecular inclusion hosts based on amino acid compound sources: design, synthesis and crystalline inclusion behavior. X-ray crystal structures of two inefficient host compounds》, and you may find the article in Journal of Inclusion Phenomena and Macrocyclic Chemistry.Product Details of 59410-82-1 The information in the text is summarized as follows:
A new design of crystalline hosts derived from amino acids, characterized by an aminoethanol functional unit or its carbonamide structural derivative and appended aromatic residues including secondary substituents, is reported. Fifteen host compounds, including (S)-2-amino-1,1-bis(4-tert-butylphenyl)-1-propanol (3) and (S)-2-(dibenzylamino)-1,1-diphenyl-1-propanol (11), were synthesized. Crystalline inclusion formation is shown and discussed with reference to structural parameters of the host mols. X-Ray crystal structures of compounds 3 and 11 have been determined in order to suggest reasons for their failure to show inclusion ability. In the experiment, the researchers used H-Phg-OEt.HCl(cas: 59410-82-1Product Details of 59410-82-1)
H-Phg-OEt.HCl(cas: 59410-82-1) belongs to esters. Esters are more polar than ethers but less polar than alcohols. Product Details of 59410-82-1 They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics