Chen, Zhi-Min; Zhang, Qing-Wei; Chen, Zhi-Hua; Li, Hui; Tu, Yong-Qiang; Zhang, Fu-Min; Tian, Jin-Miao published the artcile< Organocatalytic Asymmetric Halogenation/Semipinacol Rearrangement: Highly Efficient Synthesis of Chiral α-Oxa-Quaternary β-Haloketones>, Electric Literature of 112-63-0, the main research area is dihydropyranyl diarylmethanol cinchona alkaloid diastereoselective enantioselective halogenation semipinacol rearrangement; beta haloketone chiral halotetrahydropyranyl ketone stereoselective preparation; diastereoselective enantioselective halogenation semipinacol rearrangement catalyst cinchona alkaloid.
A novel asym. halogenation/semipinacol rearrangement reaction catalyzed by cinchona alkaloid derivatives was developed. Two types of β-haloketones (X = Br, Cl) were obtained with up to 95% yield and 99% enantiomeric excess. The desired (+) and (-) enantiomers of the β-haloketones were readily obtained.
Journal of the American Chemical Society published new progress about Aralkyl alcohols Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation) (dihydropyranyl). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Electric Literature of 112-63-0.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics