Wu, Jingjie; Bao, Fengda; Ye, Xiaoxia; Li, Juan; Jiang, Jun published the artcile< Asymmetric Construction of Highly Functionalized Cyclobutanones Bearing Three Contiguous Stereogenic Centers by an Amino Acid Salt-Catalyzed Desymmetrization Reaction>, Formula: C19H34O2, the main research area is functionalized cyclobutanone preparation; cyclobutanone keto ester desymmetrization amino acid salt catalyzed.
An amino acid salt-catalyzed direct desymmetrization of 3-substituted cyclobutanones through a direct aldol reaction under mild reaction conditions was reported. The developed method provided an array of highly functionalized cyclobutanones bearing three contiguous stereogenic centers I [R = H, CO2Et; Ar = Ph, 2-FC6H4, 2-naphthyl, etc.; n = 1,2,3] in high yields and stereoselectivities with varied functional-group compatibility. Furthermore, the obtained adducts could be smoothly converted into polyfunctional 1,4-butyrolactones with maintained enantioselectivity.
Synlett published new progress about Cyclobutanones Role: PRP (Properties), RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Formula: C19H34O2.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics