Hoelzel, Conner A.; Hu, Hang; Wolstenholme, Charles H.; Karim, Basel A.; Munson, Kyle T.; Jung, Kwan Ho; Zhang, Han; Liu, Yu; Yennawar, Hemant P.; Asbury, John B.; Li, Xiaosong; Zhang, Xin published the artcile< A General Strategy to Enhance Donor-Acceptor Molecules Using Solvent-Excluding Substituents>, Safety of Dimethyl 2,2′-azanediyldiacetate hydrochloride, the main research area is triazole donor acceptor mol substituent; amines; charge transfer; donor-acceptor systems; fluorescence; solvent effects.
While organic donor-acceptor (D-A) mols. are widely employed in multiple areas, the application of more D-A mols. could be limited because of an inherent polarity sensitivity that inhibits photochem. processes. Presented here is a facile chem. modification to attenuate solvent-dependent mechanisms of excited-state quenching through addition of a β-carbonyl-based polar substituent. The results reveal a mechanism wherein the β-carbonyl substituent creates a structural buffer between the donor and the surrounding solvent. Through computational and exptl. analyses, it is demonstrated that the β-carbonyl simultaneously attenuates two distinct solvent-dependent quenching mechanisms. Using the β-carbonyl substituent, improvements in the photophys. properties of commonly used D-A fluorophores and their enhanced performance in biol. imaging are shown.
Angewandte Chemie, International Edition published new progress about Absorption. 39987-25-2 belongs to class esters-buliding-blocks, and the molecular formula is C6H12ClNO4, Safety of Dimethyl 2,2′-azanediyldiacetate hydrochloride.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics