The direct conversion of aromatic nitro compounds to isocyanates by carbon monoxide was written by Hardy, William B.;Bennett, Robert Putnam. And the article was included in Tetrahedron Letters in 1967.Safety of 3-Cyanophenylisocyanate This article mentions the following:
PhNO2 (24.6 g.), 5 g. 5% Rh/C (dried under N at 350°), 0.4 g. anhydrous FeCl3, and 100 ml. C6H6 in a 250 ml. glass lined autoclave at 500 atm. CO agitated 5.5 hrs. at 190°, the cooled autoclave discharged under N and the mixture freed from catalyst by filtration, the presence of PhNCO shown by ir and vapor phase chromatography, and the solution distilled in vacuo gave 8.3 g. pure PhNCO, b15 57°, together with 6.2 g. residue consisting of (PhNH)2CO and (PhNHCO)2NPh. No evidence for PhN:NPh, PhN(O):NPh, or any other product was obtained by vapor phase chromatographic analysis. The nitro compounds RC6H4NO2 (R = o-Me, p-Me, m-Cl, m-CF3, and m-CN) were similarly converted to the corresponding diarylurea. The reactions were carried out at 200-1350 atm. and 150-225° in stainless steel, glass-lined, or tantalum-lined autoclaves using C6H6, PhCl, C6H12, FCl2CCF2Cl as solvents, in the presence of a catalyst system consisting of a noble metal and a Lewis acid (FeCl3, FeCl2, FeBr3, AlCl3, AlBr3, SnCl4, CuCl2, and anhydrous HCl). The noble metal was supported, unsupported, or in the form of a salt, oxide, or complex. Highest yields were obtained with Pd or Rh on Al2O3 or C with FeCl3 as co-catalyst. In the experiment, the researchers used many compounds, for example, 3-Cyanophenylisocyanate (cas: 16413-26-6Safety of 3-Cyanophenylisocyanate).
3-Cyanophenylisocyanate (cas: 16413-26-6) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Safety of 3-Cyanophenylisocyanate
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics