A Mild and Efficient Direct α-Amination of β-Dicarbonyl Compounds Using Iodosobenzene and p-Toluenesulfonamide Catalyzed by Perchlorate Zinc Hexahydrate was written by Yu, Jun;Liu, Shan-Shan;Cui, Jian;Hou, Xue-Sen;Zhang, Chi. And the article was included in Organic Letters in 2012.COA of Formula: C9H10O3S This article mentions the following:
A direct α-amination of β-dicarbonyl compounds has been achieved by using iodosobenzene (PhIO) as an oxidant and p-toluenesulfonamide (TsNH2) as an aminating reagent in the presence of a catalytic amount of perchlorate zinc hexahydrate. The present amination reaction proceeds quickly at rt (<30 min needed for most tested substrates) to provide the corresponding α-N-tosylamido β-dicarbonyl compounds in high to excellent yields. In the experiment, the researchers used many compounds, for example, Ethyl 3-oxo-3-(thiophen-2-yl)propanoate (cas: 13669-10-8COA of Formula: C9H10O3S).
Ethyl 3-oxo-3-(thiophen-2-yl)propanoate (cas: 13669-10-8) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.COA of Formula: C9H10O3S
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics