A general synthesis of oligopeptides containing an oxirane ring in the place of a peptidic bond was written by Mann, Andre;Quaranta, Laura;Reginato, Gianna;Taddei, Maurizio. And the article was included in Tetrahedron Letters in 1996.Synthetic Route of C16H24N2O4 This article mentions the following:
Mols. structurally analogous to dipeptides, containing an oxirane ring in the place of the peptide bond, can be prepared by oxidative conversion of β-hydroxy selenides obtained by Mukaiyama aldol-type reaction of N-protected β-amino α-selenyl aldehydes derived from naturally occurring amino acids. In the experiment, the researchers used many compounds, for example, (S)-tert-Butyl (1-(methoxy(methyl)amino)-1-oxo-3-phenylpropan-2-yl)carbamate (cas: 87694-53-9Synthetic Route of C16H24N2O4).
(S)-tert-Butyl (1-(methoxy(methyl)amino)-1-oxo-3-phenylpropan-2-yl)carbamate (cas: 87694-53-9) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Synthetic Route of C16H24N2O4
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics