Hypoxia-activated, small-molecule-induced gene expression was written by Collins, Sarah L.;Saha, Jaideep;Bouchez, Laure C.;Hammond, Ester M.;Conway, Stuart J.. And the article was included in ACS Chemical Biology in 2018.COA of Formula: C16H22O11 This article mentions the following:
Hypoxia, a condition of reduced oxygen, occurs in a wide variety of biol. contexts, including solid tumors and bacterial biofilms, which are relevant to human health. Consequently, the development of chem. tools to study hypoxia is vital. Here we report a hypoxia-activated, small-mol.-mediated gene expression system using a bioreductive prodrug of the inducer iso-Pr 1-thio-β-
(2S,3R,4S,5S,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 4163-60-4) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. COA of Formula: C16H22O11
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics