Chalothorn, Thidarat et al. published their research in Tetrahedron Letters in 2019 | CAS: 81245-24-1

Methyl 2-methoxy-4-methylbenzoate (cas: 81245-24-1) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Application In Synthesis of Methyl 2-methoxy-4-methylbenzoate

Synthesis and antibacterial activity of emodin and its derivatives against methicillin-resistant Staphylococcus aureus was written by Chalothorn, Thidarat;Rukachaisirikul, Vatcharin;Phongpaichit, Souwalak;Pannara, Sakawrat;Tansakul, Chittreeya. And the article was included in Tetrahedron Letters in 2019.Application In Synthesis of Methyl 2-methoxy-4-methylbenzoate This article mentions the following:

Synthesis of the antibacterial emodin (I) was improved using Friedel-Crafts acylation as a key step leading to 37% overall yield. In addition, 21 analogs were synthesized by structural modification of the hydroxyl and Me groups, as well as the aromatic ring of emodin. Antibacterial activity against methicillin-resistant Staphylococcus aureus (MRSA) and cytotoxicity against noncancerous Vero cells were evaluated. A structure-activity relationship (SAR) study indicated that the hydroxyl groups and the Me group in the emodin skeleton were crucial for anti-MRSA activity. Furthermore, the presence of an iodine atom or ethylamino group on the aromatic ring enhanced the anti-MRSA activity with higher selectivity indexes, while derivatives containing bromine, chlorine atoms or quaternary ammonium salt were as active as emodin. The quaternary ammonium group on the aromatic ring also led to non-cytotoxicity against Vero cells. In the experiment, the researchers used many compounds, for example, Methyl 2-methoxy-4-methylbenzoate (cas: 81245-24-1Application In Synthesis of Methyl 2-methoxy-4-methylbenzoate).

Methyl 2-methoxy-4-methylbenzoate (cas: 81245-24-1) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Application In Synthesis of Methyl 2-methoxy-4-methylbenzoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics