A convenient method for the synthesis of chiral N-protected 1,2-amino alcohols via the reduction of the aminoketones was written by Zhou, Zheng Hong;Tang, Yi Long;Li, Kang Ying;Liu, Bing;Tang, Chu Chi. And the article was included in Chinese Chemical Letters in 2003.Product Details of 87694-53-9 This article mentions the following:
A series of optically active N-protected 1,2-amino alcs. were synthesized via the reduction of the corresponding 浼?aminoketones starting from the readily available L-amino acids. In the experiment, the researchers used many compounds, for example, (S)-tert-Butyl (1-(methoxy(methyl)amino)-1-oxo-3-phenylpropan-2-yl)carbamate (cas: 87694-53-9Product Details of 87694-53-9).
(S)-tert-Butyl (1-(methoxy(methyl)amino)-1-oxo-3-phenylpropan-2-yl)carbamate (cas: 87694-53-9) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Esters contain a carbonyl center, which gives rise to 120鎺?C閳ユ弲閳ユ彊 and O閳ユ弲閳ユ彊 angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C閳ユ彊閳ユ弲 bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Product Details of 87694-53-9
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics