Ethanol metabolism in guinea pig: ethanol oxidation and its effect on NAD/NADH ratios, oxygen consumption, and ketogenesis in isolated hepatocytes of fed and fasted animals was written by Zahlten, Rainer N.;Nejtek, Michael E.;Jacobsen, Jan. C.. And the article was included in Archives of Biochemistry and Biophysics in 1982.HPLC of Formula: 1190-39-2 This article mentions the following:
EtOH [64-17-5]-induced decrease of the mitochondrial NAD鑱借伣[53-84-9]/NADH鑱借伣[58-68-4] ratio was prevented by the addition of 4-methylpyrazole鑱借伣[7554-65-6]. In 48-h hepatocytes, endogenous ketogenesis was enhanced by 84%. Although EtOH did not further stimulate endogenous ketogenesis, it did increase ketogenesis in the presence of octanoate鑱借伣[74-81-7] or oleate鑱借伣[112-80-1]. This effect was almost completely prevented by 4-methylpyrazole. Also, the malic鑱?em>acid鑱借伣[6915-15-7]–aspartate鑱借伣[56-84-8] shuttle was the predominant H transport system during EtOH oxidation in guinea pig liver and a quant. important role of peroxidatic oxidation of EtOH by catalase鑱借伣[9001-05-2] in liver was not supported. Thus, the syndrome of alc. ketoacidosis may be due, at least partially, to the addnl. stimulation of ketogenesis by or from EtOH during fatty acid oxidation in the fasting state. In the experiment, the researchers used many compounds, for example, malonic acid dibutyl ester (cas: 1190-39-2HPLC of Formula: 1190-39-2).
malonic acid dibutyl ester (cas: 1190-39-2) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is 绾?valerolactone.HPLC of Formula: 1190-39-2
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics