Quantitative analysis of Phthalate Esters by in-situ thermal desorption atmospheric pressure photoionization mass spectrometry using a dopant as the internal standard was written by Wang, Weimin;Jiang, Dandan;Jin, Liuyu;Wang, Pingping;Xu, Fuxing;Li, Haiyang;Ding, Chuan-Fan. And the article was included in International Journal of Mass Spectrometry in 2022.Formula: C20H26O4 This article mentions the following:
Phthalate Esters (PAEs) are a group of chems. widely used in plastic products, and they are also known as endocrine disruptors that can adversely affect the hormonal balance in humans. Since many food-contacting items, such as lunch boxes, fresh keeping film, disposable cups, are made of plastic, the PAEs can easily enter the human body through the polluted foods or drinks. Traditional anal. techniques involve laborious sample pretreatment and low-throughput anal., so it is necessary to develop techniques that can rapidly and quant. detect these compounds In this article, a miniaturized ion trap mass spectrometer (ITMS) was established firstly, then, an in-situ thermal desorption atm. pressure photoionization (in-situ TD-APPI) was designed, and the dopant was explored using for improving the sensitivity and as internal standard (IS) simultaneously in the anal. process. The in-situ TD-APPI presents good performance: (1) More than 20 times improvement in sensitivity compared with Nano-ESI for PAEs; (2) 12 kinds of phthalates were quantified with using acetone as the IS, and the LODs and LOQs ranges were found to be 0.02-1 娓璯/mL and 0.02-100 娓璯/mL, resp. The technique was also applied to the quantification of mixed solutions, and the results were validated by LC/MS. Finally, six categories of food-contacting items containing PAEs were analyzed with superficial content (ng/cm2) ranging from 0 to 6.20 ng/cm2. These results demonstrate the potential of rapid quantification of anal. of PAEs in practical plastic food-contacting items by in-situ TD-APPI. In the experiment, the researchers used many compounds, for example, Dicyclohexyl phthalate (cas: 84-61-7Formula: C20H26O4).
Dicyclohexyl phthalate (cas: 84-61-7) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Formula: C20H26O4
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics