Enolizability of S-alkyl esters of thioacetoacetic and thiomalonic acids was written by Kurgane, B.;Grinvalde, A.;Stradins, J.;Brakmane, M.;Hillers, S.. And the article was included in Zhurnal Organicheskoi Khimii in 1974.Recommanded Product: malonic acid dibutyl ester This article mentions the following:
MeCOCH2CO2R (I), MeCOCH2COSR (II), RO2CCH2CO2R (III), and RSCOCH2COSR (IV), (R = Et, CH2CH2Cl, Me2CH, PhCH2, Ph), were prepared; 6-11% I and 19-28% II were in the enol form, but III and IV existed completely in the diketo form. In the experiment, the researchers used many compounds, for example, malonic acid dibutyl ester (cas: 1190-39-2Recommanded Product: malonic acid dibutyl ester).
malonic acid dibutyl ester (cas: 1190-39-2) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Recommanded Product: malonic acid dibutyl ester
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics