Optically active 2H-azepines: synthesis and rearrangement into their 3H-isomers was written by Hamprecht, Dieter;Josten, Jakob;Steglich, Wolfgang. And the article was included in Tetrahedron in 1996.Category: esters-buliding-blocks This article mentions the following:
A general synthesis of optically active 2H-azepines I (R = Me, PhCH2, R1 = Me; R = Me, Me3CO2CH2, R1 = Bu) starting from 浼?amino acids is described. The 2H-azepines easily rearrange into the corresponding 3H-isomers II. The pungent taste of chalciporone and simple 2,7-di-Me substituted 2H-azepines is due to the 2H-azepine nucleus and is independent of the absolute configuration at C-2. In the experiment, the researchers used many compounds, for example, (S)-tert-Butyl (1-(methoxy(methyl)amino)-1-oxo-3-phenylpropan-2-yl)carbamate (cas: 87694-53-9Category: esters-buliding-blocks).
(S)-tert-Butyl (1-(methoxy(methyl)amino)-1-oxo-3-phenylpropan-2-yl)carbamate (cas: 87694-53-9) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Esters contain a carbonyl center, which gives rise to 120鎺?C閳ユ弲閳ユ彊 and O閳ユ弲閳ユ彊 angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C閳ユ彊閳ユ弲 bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Category: esters-buliding-blocks
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics