One pot cascade synthesis of fused heterocycles from furan-tethered terminal alkynes and aldehydes in the presence of amines and CuBr was written by Zhang, Yan-Yan;Hao, Jian;Shi, Min. And the article was included in Organic Chemistry Frontiers in 2015.Recommanded Product: 17920-23-9 This article mentions the following:
A one-pot protocol for the construction of complex heterocycles through furan-tethered terminal alkynes, aldehydes, amines and CuBr upon heating was developed, giving the cycloadducts in moderate to high yields along with moderate to good regioselectivities. The reactions proceed through a two-component domino reaction, including allenation and subsequent intramol. Diels-Alder reaction. A wide range of aliphatic or aromatic aldehydes and furan-tethered terminal alkynes were well-tolerated, enriching the chem. of the intramol. Diels-Alder reaction related to furan. In the experiment, the researchers used many compounds, for example, Diethyl 2-(prop-2-yn-1-yl)malonate (cas: 17920-23-9Recommanded Product: 17920-23-9).
Diethyl 2-(prop-2-yn-1-yl)malonate (cas: 17920-23-9) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Recommanded Product: 17920-23-9
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics