Synthesis of 2-thiopheneacetic acid was written by Zhang, Junlin;Cheng, Hui;Qian, Yuejun. And the article was included in Zhongguo Yiyao Gongye Zazhi in 1993.Name: Methyl 2-thienylacetate This article mentions the following:
Treatment of 2-acetylthiophene with BF3.OEt2 and Pb(OAc)4 in MeOH gave 74% Me 2-thiopheneacetate, hydrolysis of which with aqueous NaOH gave 95.7% the title compound In the experiment, the researchers used many compounds, for example, Methyl 2-thienylacetate (cas: 19432-68-9Name: Methyl 2-thienylacetate).
Methyl 2-thienylacetate (cas: 19432-68-9) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Name: Methyl 2-thienylacetate
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics