Antioxidative, anticancer, and antibacterial activities of a nanoemulsion-based gel containing Myrtus communis L. essential oil was written by Roozitalab, Ghazaal;Yousefpoor, Yaser;Abdollahi, Abbas;Safari, Mojdeh;Rasti, Fatemeh;Osanloo, Mahmoud. And the article was included in Chemical Papers in 2022.Quality Control of (E)-3,7-Dimethylocta-2,6-dien-1-yl acetate This article mentions the following:
Myrtus communis L. is a common medicinal plant with a wide range of biol. properties. In this study, an attempt was made to improve its essential oil’s antioxidant, anticancer, and antibacterial activities by preparing a nanogel dosage form. Alpha-pinene (29.7%), 1,8-cineole (25.8%), linalool (9.1%), linalool acetate (5.9%), and geranyl acetate (3.4%) were identified as five major compounds in the essential oil using GC-MS anal. Optimum nanoemulsion with a droplet size of 179 鍗?7 nm and a narrow droplet size distribution (SPAN 0.96) was gelified by the addition of CM-cellulose (3 w/v %). The rheometry anal. at shear rates of 0.1-100 1/s showed the viscosity was fully fitted with the Carreau-Yasuda model. The nanogel with IC50 132.6娓璯/mL was 4 folds more potent than the bulk essential oil (IC50: 580.8娓璯/mL) against A-375 melanoma cells. Besides, after treatment of Escherichia coli and Staphylococcus aureus with 1000娓璯/mL of the nanogel and the bulk essential oil, their growths were observed at 37.5 and 59.1% as well as 21.4 and 40.6%. Besides, antioxidant activity was investigated using DPPH assay; the nanogel was significantly more potent (P < 0.001) than that of bulk essential oil at all examined concentrations (62.6-1000娓璯/mL). Furthermore, polyethylene oxide-gelatin electrospun nanofibers (diameter of 359 鍗?36 nm) with no effects on the cancer cell and the bacterial growth were proposed as lesion dressing after-treatment with the nanogel. Therefore, the stained nanofiber with the nanogel could be considered a natural potent anticancer and antibacterial agent in vivo study. In the experiment, the researchers used many compounds, for example, (E)-3,7-Dimethylocta-2,6-dien-1-yl acetate (cas: 105-87-3Quality Control of (E)-3,7-Dimethylocta-2,6-dien-1-yl acetate).
(E)-3,7-Dimethylocta-2,6-dien-1-yl acetate (cas: 105-87-3) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Quality Control of (E)-3,7-Dimethylocta-2,6-dien-1-yl acetate
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics