Resolution of secondary alcohols via Carica papaya lipase-catalyzed enantioselective acylation was written by Miyazawa, Toshifumi;Houhashi, Mika;Inoue, Yusuke;Murashima, Takashi;Yamada, Takashi. And the article was included in Biotechnology Letters in 2008.Application of 15399-05-0 This article mentions the following:
The Carica papaya lipase-catalyzed acylation of benzylcarbinols with vinyl hexanoate proceeded smoothly and enantiospecifically (E > 200), affording the R-esters and leaving the S-alcs. intact. Thus, this plant lipase proved to be a promising biocatalyst for the resolution of alcs. as well as for that of carboxylic acids reported earlier. In the experiment, the researchers used many compounds, for example, Ethyl 2-hydroxy-3-phenylpropanoate (cas: 15399-05-0Application of 15399-05-0).
Ethyl 2-hydroxy-3-phenylpropanoate (cas: 15399-05-0) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Application of 15399-05-0
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics