Synthesis, characterization and biological activities of new bis-1,3,4-oxadiazoles was written by Malghe, Yuvraj S.;Thorat, Varsha V.;Chowdhary, Abhay S.;Bobade, Anil S.. And the article was included in Journal of Chemical and Pharmaceutical Research in 2015.Formula: C12H22O4 This article mentions the following:
A series of 1,n-bis[5-(3-methoxy-4-hydroxy-5-nitrophenyl)-1,3,4-oxadiazol-2-yl]alkanes/benzene was synthesized. Condensation of different dihydrazides with 5-nitrovanillin gave corresponding dihydrazones. Dihydrazones on oxidative cyclization using chloramine-T yielded the corresponding bis-1,3,4-oxadiazole derivatives Structures of newly synthesized compounds were established using FTIR, 1H NMR and elemental anal. All compounds were screened for their anti-inflammatory activities. IC50 values revealed that newly synthesized compounds exhibited better anti-inflammatory activities. Representative samples were studied for cytotoxicity. Results of cytotoxicity revealed that compounds exhibited moderate cytotoxicity. In the experiment, the researchers used many compounds, for example, Dimethyl decanedioate (cas: 106-79-6Formula: C12H22O4).
Dimethyl decanedioate (cas: 106-79-6) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Formula: C12H22O4
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics