Ethyl 2-hydroxy-3-phenylpropanoate (cas: 15399-05-0) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Esters contain a carbonyl center, which gives rise to 120鎺?C閳ユ弲閳ユ彊 and O閳ユ弲閳ユ彊 angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C閳ユ彊閳ユ弲 bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Reference of 15399-05-0
An inquiry into the enzyme-catalyzed hydrolysis of leucine ethyl ester by chymotrypsin was written by Goldenberg, Harry;Goldenberg, Vivian;McLaren, A. D.. And the article was included in Biochimica et Biophysica Acta in 1951.Reference of 15399-05-0 This article mentions the following:
Ethyl esters of L-leucine and L-灏?phenyllactic acid and acetyl-DL-phenylalanine hydrazide were slowly hydrolyzed by chymotrypsin. Hydrolysis of ethyl esters of L-phenylalanine, L-tyrosine, acetyl-DL-phenylalanine, chloroacetyl-DL-phenylalanine, and of acetyl-DL-phenylalanine thioethyl ester was more rapid. In the experiment, the researchers used many compounds, for example, Ethyl 2-hydroxy-3-phenylpropanoate (cas: 15399-05-0Reference of 15399-05-0).
Ethyl 2-hydroxy-3-phenylpropanoate (cas: 15399-05-0) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Esters contain a carbonyl center, which gives rise to 120鎺?C閳ユ弲閳ユ彊 and O閳ユ弲閳ユ彊 angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C閳ユ彊閳ユ弲 bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Reference of 15399-05-0
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics