Stereospecific synthesis of chiral tertiary alkyl aryl ethers via Mitsunobu reaction with complete inversion of configuration was written by Shi, Yao-Jun;Hughes, David L.;McNamara, James M.. And the article was included in Tetrahedron Letters in 2003.Recommanded Product: 19444-23-6 This article mentions the following:
Mitsunobu reaction of (S)-EtCMe(OH)COOMe with 4-(benzyloxy)phenol provides (R)-4-PhCH2OC6H4OCMeEtCOOMe in moderate yield at elevated temperatures (80-100°). The SN2 displacement pathway is evident by complete inversion of the (S)-alc. to the (R)-ether. Several analogous reactions were also performed. In the experiment, the researchers used many compounds, for example, Benzyl 2-hydroxy-2-methylpropanoate (cas: 19444-23-6Recommanded Product: 19444-23-6).
Benzyl 2-hydroxy-2-methylpropanoate (cas: 19444-23-6) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Recommanded Product: 19444-23-6
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics