Non-metal Lewis acid-catalyzed cross-Claisen condensation for β-keto esters was written by Zhang, Tianyu;Yang, Zhenkun;Zhou, Dapeng;Meng, Fuliang;Han, Zhengyu;Huang, Hai. And the article was included in Organic & Biomolecular Chemistry in 2021.COA of Formula: C10H11FO2 This article mentions the following:
A new catalytic and highly chemoselective cross-Claisen condensation of esters was disclosed. In the presence of TBSNTf2 as a non-metal Lewis acid, various esters can undergo cross-Claisen condensation to for/m β-keto esters which are important building blocks. Compared with the traditional Claisen condensation, this process, employing silyl ketene acetals (SKAs) as carbonic nucleophiles to achieve cross-Claisen condensation, requires mild conditions and has good tolerance of functional groups. In the experiment, the researchers used many compounds, for example, Ethyl 2-(4-fluorophenyl)acetate (cas: 587-88-2COA of Formula: C10H11FO2).
Ethyl 2-(4-fluorophenyl)acetate (cas: 587-88-2) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.COA of Formula: C10H11FO2
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics