Photolactonization: a novel synthetic entry to macrolides was written by Quinkert, Gerhard;Billhardt, Uta Maria;Jakob, Harald;Fischer, Gerd;Glenneberg, Juergen;Nagler, Peter;Autze, Volker;Heim, Nana;Wacker, Manfred. And the article was included in Helvetica Chimica Acta in 1987.COA of Formula: C11H14O3 This article mentions the following:
o-Quinol acetates, hydroxyalkylated at C-6 (e.g., I), are easily accessible from simple phenols by Wessely acetoxylation (preferentially catalyzed by BF3). On UV irradiation (in the presence of an appropriate tertiary amine), they are smoothly converted to macrocyclic lactones, e.g., II. Subtle conditions were elaborated to lead to high overall yields, and the scope of the conversion of phenols to macrolides was elucidated. In the experiment, the researchers used many compounds, for example, Methyl 4-(2-hydroxyphenyl)butanoate (cas: 93108-07-7COA of Formula: C11H14O3).
Methyl 4-(2-hydroxyphenyl)butanoate (cas: 93108-07-7) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.COA of Formula: C11H14O3
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics