Microwave-assisted palladium-catalyzed isonitrile insertion in 2-bromophenylureas for efficient synthesis of 4-substituted imino 4H-benzo[d][1,3]oxazin-2-amines was written by Pandey, Garima;Batra, Sanjay. And the article was included in RSC Advances in 2015.Recommanded Product: 16413-26-6 This article mentions the following:
A general route to the synthesis of 4-substituted imino 4H-benzo[d][1,3]oxazin-2-amines via palladium-catalyzed isonitrile insertion in 2-bromophenylureas succeeded by a C-O cross-coupling of the intermediate imidoylpalladium species under microwave irradiation was reported. In the experiment, the researchers used many compounds, for example, 3-Cyanophenylisocyanate (cas: 16413-26-6Recommanded Product: 16413-26-6).
3-Cyanophenylisocyanate (cas: 16413-26-6) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Recommanded Product: 16413-26-6
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics