Substituent effects on the McLafferty rearrangement of methyl 4-phenylbutyrates was written by Kingston, David G. I.;Tannenbaum, Harvey P.. And the article was included in Chemical Communications (London) in 1968.Category: esters-buliding-blocks This article mentions the following:
The McLafferty rearrangement of substituted p-RC6H4(CH2)3CO2Me (I) does not obey the standard equation for mass spectrometric reactions, but rather a modified form. The intensity of the radical ion [HOC(:CH2)OMe]· shows a considerable substituent effect based on the fact that substituents alter the relative proportions of mol. ions of I capable of decomposition (with the pos.charge localized on the carbonyl group) and those not capable of decomposition(with the pos. charge delocalized in the aromatic ring). The observed substituent effects are due, therefore, to a combination of a substituent effect on the energy of the transition state leading to the ions formed and a substituent effect on the fraction of mol. ions capable of undergoing rearrangement. In the experiment, the researchers used many compounds, for example, Methyl 4-(4-aminophenyl)butanoate (cas: 20637-09-6Category: esters-buliding-blocks).
Methyl 4-(4-aminophenyl)butanoate (cas: 20637-09-6) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Category: esters-buliding-blocks
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics