Ruthenium-Catalyzed Reductive Arylation of N-(2-Pyridinyl)amides with Isopropanol and Arylboronate Esters was written by Ronson, Thomas O.;Renders, Evelien;Van Steijvoort, Ben F.;Wang, Xubin;Wybon, Clarence C. D.;Prokopcova, Hana;Meerpoel, Lieven;Maes, Bert U. W.. And the article was included in Angewandte Chemie, International Edition in 2019.Recommanded Product: Methyl 2-aminonicotinate This article mentions the following:
A new three-component reductive arylation of amides with stable reactants (iPrOH and arylboronate esters), making use of a 2-pyridinyl (Py) directing group, is described. The N-Py-amide substrates are readily prepared from carboxylic acids and PyNH2, and the resulting N-Py-1-arylalkanamine reaction products are easily transformed into the corresponding chlorides by substitution of the HN-Py group with HCl. The 1-aryl-1-chloroalkane products allow substitution and cross-coupling reactions. Therefore, a general protocol for the transformation of carboxylic acids into a variety of functionalities is obtained. The Py-NH2 byproduct can be recycled. In the experiment, the researchers used many compounds, for example, Methyl 2-aminonicotinate (cas: 14667-47-1Recommanded Product: Methyl 2-aminonicotinate).
Methyl 2-aminonicotinate (cas: 14667-47-1) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Recommanded Product: Methyl 2-aminonicotinate
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics