Dudouit, Fabienne et al. published their research in Bioorganic & Medicinal Chemistry Letters in 2000 | CAS: 5930-92-7

Ethyl 4-nitro-1H-pyrrole-2-carboxylate (cas: 5930-92-7) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Application of 5930-92-7

Synthesis, DNA binding, topoisomerases inhibition, and cytotoxic properties of 4-arylcarboxamidopyrrolo-2-carboxyanilides was written by Dudouit, Fabienne;Goossens, Jean-Francois;Houssin, Raymond;Henichart, Jean-Pierre;Colson, Pierre;Houssier, Claude;Gelus, Nathalie;Bailly, Christian. And the article was included in Bioorganic & Medicinal Chemistry Letters in 2000.Application of 5930-92-7 This article mentions the following:

N-aryl-4-benzamidopyrrolecarboxamides I (R = H, Me, PhCH2) were synthesized and evaluated for their capacities to bind to specific sequences within the minor groove of DNA and to inhibit human topoisomerases I and II in vitro. The cytotoxicity of the drugs correlates with their DNA binding affinities. Compounds I (R = Me, PhCH2) stabilize topoisomerase I-DNA complexes. In the experiment, the researchers used many compounds, for example, Ethyl 4-nitro-1H-pyrrole-2-carboxylate (cas: 5930-92-7Application of 5930-92-7).

Ethyl 4-nitro-1H-pyrrole-2-carboxylate (cas: 5930-92-7) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Application of 5930-92-7

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics