Month: January 2023

Identification of key aromas of Chinese muskmelon and study of their formation mechanisms was written by Xiao, Zuobing;Xie, Yongheng;Niu, Yunwei;Zhu, Jiancai. And the article was included in European Food Research and Technology in 2021.Safety of Methyl2-methylbutyrate This article mentions the following:

The volatile compounds found in melons (Cucumis melo L.) obtained from three cultivars [Jiashi (JS), Xizhoumi17 (XZM) and Minqin (MQ)] were comprehensively analyzed by gas chromatog.-olfactometry (GC-O), gas chromatog.-mass spectrometry (GC-MS), and GC-flame photometric detection (GC-FPD). The result showed that 46, 45 and 69 volatile compounds were detected in XZM, JS and MQ samples by GC-MS, resp. Besides, 6, 8 and 9 sulfur compounds were detected by GC-FPD, resp. Di-Me sulfide, 1-propanethiol, 3-mercapto-3methylbutanol, 3-methyl-2-buten-1-thiol were detected for the first time in melon. 25 key aroma compounds were identified in MQ muskmelon by omission tests, among which (Z)-6-nonenal, (Z)-6-nonen-1-ol, 3-methylbutanal, 2-methylbutyl acetate, hexanal and Me thioacetate were particularly important. The interaction between three aroma compounds containing nine-carbon straight-chain structure and five thioesters in MQ muskmelon was studied by comparing their olfactory threshold and OAV values. Among the 18 binary mixtures, 8 mixtures showed a synergistic effect, 2 mixtures presented an additive effect, 2 mixtures showed no interaction, 6 mixtures exhibited a masking effect. There is a synergistic effect between (Z)-6-nonenal, (Z)-6-nonen-1-ol and (E, Z)-3,6-nonadien-1-ol, the aroma intensity of the mixture can be predicted by modified vector model. In the experiment, the researchers used many compounds, for example, Methyl2-methylbutyrate (cas: 868-57-5Safety of Methyl2-methylbutyrate).

Methyl2-methylbutyrate (cas: 868-57-5) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Safety of Methyl2-methylbutyrate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Dynamic kinetic asymmetric transformation (DYKAT) by combined amine- and transition-metal-catalyzed enantioselective cycloisomerization was written by Zhao, Gui-Ling;Ullah, Farman;Deiana, Luca;Lin, Shuangzheng;Zhang, Qiong;Sun, Junliang;Ibrahem, Ismail;Dziedzic, Pawel;Cordova, Armando. And the article was included in Chemistry – A European Journal in 2010.Computed Properties of C10H14O4 This article mentions the following:

The first examples of one-pot highly chemo- and enantioselective dynamic kinetic asym. transformations (DYKATs) involving α,β-unsaturated aldehydes and propargylated carbon acids are presented. These DYKATs, which proceed by a combination of catalytic iminium activation, enamine activation, and Pd⁰-catalyzed enyne cycloisomerization, give access to functionalized cyclopentenes e. g., I with up to 99 % ee and can be used for the generation of all-carbon quaternary stereocenters. In the experiment, the researchers used many compounds, for example, Diethyl 2-(prop-2-yn-1-yl)malonate (cas: 17920-23-9Computed Properties of C10H14O4).

Diethyl 2-(prop-2-yn-1-yl)malonate (cas: 17920-23-9) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Computed Properties of C10H14O4

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Compounds with antineoplastic activity. LXXXII. 5,5-Disubstituted barbituric acids and their analogs was written by Kotva, Rudolf;Krepelka, Jiri;Semonsky, Miroslav. And the article was included in Collection of Czechoslovak Chemical Communications in 1983.Recommanded Product: 17920-23-9 This article mentions the following:

Barbituric acid derivatives I [R = Me, Et, Pr, Bu, Ph, CH₂:CHCH₂, R¹ = (CH₂)₄CO₂H; R = Et, Bu, R¹ = (CH₂)₄CONHCH₂CO₂Et], II (R = Me, Pr), and III [R = CH₂:CHCH₂, (CH₂)₄CO₂H, R¹ = (CH₂)₄CO₂H; R = HCCCH₂, (CH₂)₄CO₂Et] were prepared by cyclocondensation of (EtO₂C)₂CR(CH₂)₄CO₂Et with urea, thiourea, and guanidine. Compound III [R = CH₂:CHCH₂, R¹ = (CH₂)₄CO₂H] enhanced the action of 5-fluorouracil on leukemia in mice by 22% at a dose at 200 mg/kg. In the experiment, the researchers used many compounds, for example, Diethyl 2-(prop-2-yn-1-yl)malonate (cas: 17920-23-9Recommanded Product: 17920-23-9).

Diethyl 2-(prop-2-yn-1-yl)malonate (cas: 17920-23-9) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Recommanded Product: 17920-23-9

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Homoallylic rearrangement with participating groups. III. Acid-catalyzed isomerization of cis- and trans-2-[2,2′-dimethyl-3′-(but-3”-enyl)]-cyclopropyl-2-propanols was written by Julia, Marc;Descoins, Charles. And the article was included in Bulletin de la Societe Chimique de France in 1970.Recommanded Product: Diethyl isobutylmalonate This article mentions the following:

Treatment of the title alcs. (I) with HCO2H gave appreciable amount of the participation product trans-II and (III), which on protonation gave quant. II. Substitution of the cyclopropyl ring favored the formation of II, due to steric effects. The stereochemistry and mechanisms of acid isomerizations of I are discussed. In the experiment, the researchers used many compounds, for example, Diethyl isobutylmalonate (cas: 10203-58-4Recommanded Product: Diethyl isobutylmalonate).

Diethyl isobutylmalonate (cas: 10203-58-4) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Recommanded Product: Diethyl isobutylmalonate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Synthesis of Thiazoles and Isothiazoles via Three-Component Reaction of Enaminoesters, Sulfur, and Bromodifluoroacetamides/Esters was written by Ma, Xingxing;Yu, Xiaoxia;Huang, Hua;Zhou, Yao;Song, Qiuling. And the article was included in Organic Letters in 2020.Reference of 33166-79-9 This article mentions the following:

A three-component strategy for the synthesis of thiazoles, e.g., I, and isothiazoles, e.g., II, has been developed by employing enaminoesters, fluorodibromoamides/ester, and sulfur. The thiazoles and isothiazoles were formed via two C-F bond cleavages along with the formation of new C-S, C-N, and N-S bonds. The strategy provides high selectivity for the synthesis of thiazoles/isothiazoles, which have vital applications in drug discovery and development. In the experiment, the researchers used many compounds, for example, Ethyl 3-oxo-3-(m-tolyl)propanoate (cas: 33166-79-9Reference of 33166-79-9).

Ethyl 3-oxo-3-(m-tolyl)propanoate (cas: 33166-79-9) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Reference of 33166-79-9

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Indium-catalyzed, novel route to β,β-disubstituted indanones via tandem Nakamura addition-hydroarylation-decarboxylation sequence was written by Rajesh, Nimmakuri;Prajapati, Dipak. And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2015.Computed Properties of C12H14O3 This article mentions the following:

A novel method for the construction of β,β-disubstituted indanones was developed via tandem Nakamura addition-hydroarylation-decarboxylation process. Indium(III) triflate was demonstrated as a versatile multitasking catalyst, which catalyzes three different chem. transformations under one-pot conditions. In the experiment, the researchers used many compounds, for example, Ethyl 3-oxo-3-(m-tolyl)propanoate (cas: 33166-79-9Computed Properties of C12H14O3).

Ethyl 3-oxo-3-(m-tolyl)propanoate (cas: 33166-79-9) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Computed Properties of C12H14O3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Synthesis, characterization and application of two new lariat crown ethers in construction of PVC membrane, coated wire and coated graphite electrodes: application to flow injection potentiometry was written by Shamsipur, Mojtaba;Dezaki, Abbas Shirmardi;Akhond, Morteza;Sharghi, Hashem;Khalife, Reza. And the article was included in International Journal of Environmental Analytical Chemistry in 2011.Quality Control of Dimethyl decanedioate This article mentions the following:

Two lariat crown ethers, 7-(2-Hydroxy-5-methylbenzyl)-5,6,7,8,9,10-hexahydro-2H-benzo[b][1,4,7,10,13]pentadecine-3,11(4H,12H)dione (L1) and, 7-(5-tert-butyl-2-hydroxybenzyl)-5,6,7,8,9,10-hexahydro-2H-benzo[b][1,4,7,10,13]dioatriazacyclopentadecine-3,11(4H,12H)dione (L2) were synthesized, characterized and used as active components for fabrication of PVC membrane electrode (PME), coated graphite electrode (CGE) and coated wire electrodes (CWE) for sensing Co²⁺ ion. Potassium tetrakis(p-cholorophenyl) borate(KTpClPB) and o-nitrophenyloctyl ether (o-NPOE) were added in a PVC matrix. The two lariat ethers were tested, L1 showed better electrode characteristics than L2. The electrodes exhibited linear Nernstian responses to Co²⁺ ion in the linear concentration range of 3.3 × 10^-6-1.9 × 10^-2 M (for PME), 2.3 × 10^-7-7.9 × 10^-2 M (for CWE), and 5.0 × 10^-8-1.2 × 10^-2 M (for CGE). The CGE was used as a proper detection system in flow-injection potentiometry (FIP) with a linear Nernstian range of 2.3 × 10^-7-1.2 × 10^-2 M over a pH range of 3.2 to 8.0; the limit of detection for PME, CWE, CGE, and CGE-FIP systems are 1.2 × 10^-6, 2.5 × 10^-7, 3.5 × 10^-8 and 1.0 × 10^-7 M, resp. The electrodes revealed fairly good discriminating ability towards Co²⁺ in comparison with a large number of alkali, alk. earth, transition and heavy metal ions. The electrodes are chem. inert, showing fast response time of <5 s, and could be used practically over a period of 1 mo. CGE also was used for measurement of Co²⁺ in binary mixtures In the experiment, the researchers used many compounds, for example, Dimethyl decanedioate (cas: 106-79-6Quality Control of Dimethyl decanedioate).

Dimethyl decanedioate (cas: 106-79-6) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Quality Control of Dimethyl decanedioate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Oxidation of oleic acid by mercuric oxide was written by Varlamov, V. S.. And the article was included in Trudy Vsesoyuz. Nauch.-Issledovatel. Inst. Zhirov in 1957.Computed Properties of C11H20O4 This article mentions the following:

Oleic acid (I) was oxidized by heating and stirring the acid and HgO (1 mole HgO per mole of acid) to 280° (10 hrs., CO₂ atm.) and then cooling the mixture to about 20°. The obtained mass was treated with dilute HCl to decompose formed Hg salts of I, washed with H₂O, and dried in vacuo (CO₂ atm.). In this reaction, metallic Hg separated. It was established that the oxidation formed hydroxyl groups, which led to formation of hydroxy acids. Insignificant lowering of the iodine number showed that CH₂ groups were oxidized in preference to CH: CH groups, which was explained by the high activity of atomic O and also by a large number of methylene groups. In the experiment, the researchers used many compounds, for example, malonic acid dibutyl ester (cas: 1190-39-2Computed Properties of C11H20O4).

malonic acid dibutyl ester (cas: 1190-39-2) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Computed Properties of C11H20O4

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Reactions of ethyl cinnamates with arylacetamides was written by Shandala, Mowafak Y.;Al-Khashab, Abdul-Ilah Y.;Afzal, M.;Ahmad, Shakir S.. And the article was included in Journal of Heterocyclic Chemistry in 1980.Related Products of 584-74-7 This article mentions the following:

Treating 4-RC₆H₄CH:CHCO₂Et (I; R = H, Cl, Me) with R¹C₆H₄CH₂CONH₂ (II; R¹ = H, 2-, 3-, 4-F, 3-Cl) gave the corresponding 2,6-diketo-3,4-diarylpiperidine III in addition to the corresponding 4-RC₆H₄CH:CHCONH₂ and R¹C₆H₄CH₂CO₂Et. The latter two are formed from the intermediates of the Claisen condensation of the reactants. Condensation of I (R = MeO) with II gave only p-methoxycinnamide in quant yields with the corresponding arylacetates. In the experiment, the researchers used many compounds, for example, Ethyl 2-fluorophenylacetate (cas: 584-74-7Related Products of 584-74-7).

Ethyl 2-fluorophenylacetate (cas: 584-74-7) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Related Products of 584-74-7

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Synthesis of 2,3-bis(benzoyl)butanedioic acid 1,4-diethyl ester derivatives via cerium ammonium nitrate-mediated oxidative coupling reaction of β-oxobenzenepropanoic acid esters was written by Song, Jia-Nan;Li, Xin-Sheng;Xu, Dong-Cheng;Cai, Ling-Ling. And the article was included in Youji Huaxue in 2008.Category: esters-buliding-blocks This article mentions the following:

A method for the synthesis of the above-mentioned title compounds (diketone dimers) is reported here. A mild method for preparation of 1,4-diketone via an intermol. coupling of substituted aryl β-keto esters by use of cerium ammonium nitrate in CH₃CN/H₂O is described. The procedure provided a convenient method for the synthesis of such 1,4-diketones in up to 92% yields. The reaction mechanism was discussed. In the experiment, the researchers used many compounds, for example, Ethyl 3-oxo-3-(m-tolyl)propanoate (cas: 33166-79-9Category: esters-buliding-blocks).

Ethyl 3-oxo-3-(m-tolyl)propanoate (cas: 33166-79-9) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Category: esters-buliding-blocks

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics