The key food odorant receptive range of broadly tuned receptor OR2W1 was written by Haag, Franziska;Di Pizio, Antonella;Krautwurst, Dietmar. And the article was included in Food Chemistry in 2022.Reference of 706-14-9 This article mentions the following:
Mammals perceive a multitude of odorants by their chem. sense of olfaction, a high-dimensional stimulus-detection system, with hundreds of narrowly or broadly tuned receptors, enabling pattern recognition by the brain. Cognate receptor-agonist information, however, is sparse, and the role of broadly tuned odorant receptors for encoding odor quality remains elusive. Here, we screened IL-6-HaloTag-OR2W1 and haplotypes against 187 out of 230 defined key food odorants using the GloSensor system in HEK-293 cells, yielding 48 new agonists. Altogether, key food odorants represent about two-thirds of now 153 reported agonists of OR2W1, the highest number of agonists known for a mammalian odorant receptor. In summary, we characterized OR2W1 as a human odorant receptor, with a chem. diverse but exclusive receptive range, complementary to chem. subgroups covered by evolutionary younger, highly selective receptors. Our data suggest OR2W1 to be suited for participating in the detection of many foodborne odorants. In the experiment, the researchers used many compounds, for example, 5-Hexyldihydrofuran-2(3H)-one (cas: 706-14-9Reference of 706-14-9).
5-Hexyldihydrofuran-2(3H)-one (cas: 706-14-9) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Reference of 706-14-9
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