Cascade iodination-fluorination synthesis of 2-fluorothiophene and 5-fluoro-2-thienyliodonium salts was written by Onys’ko, Petro P.;Kim, Tetyana V.;Kiseleva, Olena I.;Rassukana, Yuliya V.;Gakh, Andrei A.. And the article was included in Journal of Fluorine Chemistry in 2009.Recommanded Product: 19432-68-9 This article mentions the following:
The synthesis of F-containing 2-thienyliodonium salts was accomplished using cascade iodination-fluorination. Thus, thiophene is converted to bis(2-thienyl)iodonium hexafluorophosphate using electrophilic iodination. Upon heating with KF, this salt undergoes regioselective fluorination producing 2-fluorothiophene. Subsequent iodination yields fluorothienyliodonium salts. In the experiment, the researchers used many compounds, for example, Methyl 2-thienylacetate (cas: 19432-68-9Recommanded Product: 19432-68-9).
Methyl 2-thienylacetate (cas: 19432-68-9) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Recommanded Product: 19432-68-9
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics