Month: December 2022

Chemistry of nitro esters. XVII. Production of mesoxalic acid esters was written by Kochergin, P. M.;Titkova, R. M.. And the article was included in Zhurnal Organicheskoi Khimii in 1994.Name: malonic acid dibutyl ester This article mentions the following:

The preparation of mesoxalic acid esters from monobromomalonates and silver nitrate is described. Thus, bromination of di-Et malonate gave 85% di-Et bromomalonate (I) and 4% di-Et dibromomalonate. I with AgNO₃ in anhydrous EtOH gave AgBr and 77% di-Et mesoxalate via intermediate O₂NOCH(CO₂Et)₂. In the experiment, the researchers used many compounds, for example, malonic acid dibutyl ester (cas: 1190-39-2Name: malonic acid dibutyl ester).

malonic acid dibutyl ester (cas: 1190-39-2) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Name: malonic acid dibutyl ester

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Combined effects of tangerine oil vapour mixed with banana flavor to enhance the quality and flavor of ‘Hom Thong’ bananas and evaluating consumer acceptance and responses using electroencephalography (EEG) was written by Saengwong-Ngam, Ravinun;Koomhin, Phanit;Songsamoe, Sumethee;Matan, Nirundorn;Matan, Narumol. And the article was included in Journal of Food Science and Technology (New Delhi, India) in 2022.SDS of cas: 659-70-1 This article mentions the following:

The objectives of this study were to investigate the effect of tangerine oil (TO) at 25, 50 and 75μL mixed with banana flavor (BF) at 25, 50 and 75μL to protect the quality and enhance the flavor of bananas. Then, 25μL TO + BF 50μL were selected for studying the quality of bananas stored at 13°C ± 2°C for 7 days, and was used to test consumer brain responses using an electroencephalog. (EEG). Results showed that mold grew and decomposition occurred in 10 and 50% of the 25μL TO + 50μL BF mixture and control, resp., after 7 days. Furthermore, this ratio increased ripening by having higher L*, b*, firmness and total soluble solid than the control (p < 0.05), whereas titratable acidity and pH were maintained (p > 0.05). The EEG demonstrated that consumption of TO-treated banana could increase brain alertness using stimulating the beta wave activity on banana stimulations for human brain. Limonene, one of the main components of TO, was found in the flesh of treated banana after storage for 4 wk and possibly interacted with other components to improve antifungal activity and brain response. In the experiment, the researchers used many compounds, for example, Isopentyl 3-methylbutanoate (cas: 659-70-1SDS of cas: 659-70-1).

Isopentyl 3-methylbutanoate (cas: 659-70-1) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.SDS of cas: 659-70-1

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Large pores generated by the combination of different inorganic units in a zinc hydroxide ethynylene diisophthalate MOF was written by Hausdorf, Steffen;Seichter, Wilhelm;Weber, Edwin;Mertens, Florian O. R. L.. And the article was included in Dalton Transactions in 2009.Safety of Dimethyl 5-ethynylisophthalate This article mentions the following:

A 5,5′-ethynylenediisophthalic acid linker mol. was synthesized and used to form a zinc carboxylate-based metal organic framework (MOF) with very large pores and unit cell volume resulting from the unusual combination of structurally different inorganic units forming the secondary building blocks (SBUs). The structure is the first zinc hydroxide carboxylate structure where the inorganic units do not form layers or ribbons but isolated islands. The structure forms true pores with a significantly narrowed pore entry similar to zeolites. The pores are, thus, not created simply by intersecting channels as in most other MOF structures. Although the pore shape is highly asym. the spherical free volume is with 10.8 Å still large. The stability of the SBUs in respect to exchange and removal of coordinated solvent mols. was studied. In the experiment, the researchers used many compounds, for example, Dimethyl 5-ethynylisophthalate (cas: 313648-56-5Safety of Dimethyl 5-ethynylisophthalate).

Dimethyl 5-ethynylisophthalate (cas: 313648-56-5) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Safety of Dimethyl 5-ethynylisophthalate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Shifting Sol-Gel Phase Diagram of a Doubly Thermosensitive Hydrophilic Diblock Copolymer Poly(methoxytri(ethylene glycol) acrylate-co-acrylic acid)-b-poly(ethoxydi(ethylene glycol) acrylate-co-acrylic acid) in Aqueous Solution was written by Jin, Naixiong;Zhang, Hao;Jin, Shi;Dadmun, Mark D.;Zhao, Bin. And the article was included in Macromolecules (Washington, DC, United States) in 2012.Formula: C14H12S2 This article mentions the following:

This article reports that the C-shaped sol-gel phase diagram of a doubly thermosensitive hydrophilic diblock copolymer with each block containing a small amount of weak acid groups in aqueous solution in the moderate concentration range can be readily and reversibly shifted by changing the solution pH. The diblock copolymer, poly(methoxytri(ethylene glycol) acrylate-co-acrylic acid)-b-poly(ethoxydi(ethylene glycol) acrylate-co-acrylic acid) (P(TEGMA-co-AA)-b-P(DEGEA-co-AA)), was synthesized by reversible addition-fragmentation chain transfer polymerization and postpolymn. modification. A 20 wt % aqueous solution of P(TEGMA-co-AA)-b-P(DEGEA-co-AA) with pH of 3.29 underwent sol-to-gel, gel-to-sol, and clear sol-to-cloudy sol transitions at 17° (T_sol-gel), 38° (T_gel-sol), and 55° (T_clouding), resp., upon heating. With the increase of pH, all transition temperatures shifted to high values; for instance, the T_sol-gel, T_gel-sol, and T_clouding were 20, 45, and 63°, resp., at pH = 5.10, and 28, 52, and 77°, resp., at pH = 5.79. Using vial inversion tests, we mapped out sol-gel phase diagrams of the diblock copolymer in aqueous solutions at three pH values (3.29, 5.10, and 5.79, measured at ∼0°); the whole sol-gel phase diagram shifted upward with the increase of pH. When the pH was lowered from 5.79 to 5.10, the diagram shifted back, though there was a 1° difference at each selected concentration, compared with the original curve of pH = 5.10. The tunability of sol-gel-sol-clouding transitions stemmed from the pH dependences of thermosensitive properties of two blocks, which were confirmed by a dynamic light scattering study. The results from small-angle X-ray scattering experiments indicated that spherical micelles of P(TEGMA-co-AA)-b-P(DEGEA-co-AA) in 20 wt % aqueous solutions at selected pH and temperatures were packed into crystalline structures, either body-centered cubic or face-centered cubic, in the gel states. In the experiment, the researchers used many compounds, for example, Benzyl benzodithioate (cas: 27249-90-7Formula: C14H12S2).

Benzyl benzodithioate (cas: 27249-90-7) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Formula: C14H12S2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

A highly porous NbO type metal-organic framework constructed from an expanded tetracarboxylate was written by Cai, Jianfeng;Rao, Xingtang;He, Yabing;Yu, Jancan;Wu, Chuande;Zhou, Wei;Yildirim, Taner;Chen, Banglin;Qian, Guodong. And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2014.Name: Dimethyl 5-ethynylisophthalate This article mentions the following:

A novel NbO type microporous metal-organic framework Cu₂L (ZJU-32 (5); H₄L (4) = 5′-((3,5-dicarboxyphenyl)ethynyl)-[1,1′:3′,1”-terphenyl]-4,4”-dicarboxylic acid) constructed from an elaborately designed tetratopic ligand was solvothermally synthesized and structurally characterized. The activated ZJU-32a exhibits high permanent porosity with the Brunauer-Emmett-Teller (BET) surface area of 3831 m² g^-1 and the pore volume of 1.482 cm³ g^-1, enabling it to be a promising material for both methane storage and carbon dioxide capture at room temperature In the experiment, the researchers used many compounds, for example, Dimethyl 5-ethynylisophthalate (cas: 313648-56-5Name: Dimethyl 5-ethynylisophthalate).

Dimethyl 5-ethynylisophthalate (cas: 313648-56-5) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Name: Dimethyl 5-ethynylisophthalate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Synthesis, biological evaluation and molecular investigation of fluorinated peroxisome proliferator-activated receptors α/γ dual agonists was written by Fracchiolla, Giuseppe;Laghezza, Antonio;Piemontese, Luca;Parente, Mariagiovanna;Lavecchia, Antonio;Pochetti, Giorgio;Montanari, Roberta;Di Giovanni, Carmen;Carbonara, Giuseppe;Tortorella, Paolo;Novellino, Ettore;Loiodice, Fulvio. And the article was included in Bioorganic & Medicinal Chemistry in 2012.Category: esters-buliding-blocks This article mentions the following:

PPARs are transcription factors that govern lipid and glucose homeostasis and play a central role in cardiovascular disease, obesity, and diabetes. Thus, there is significant interest in developing new agonists for these receptors. Given that the introduction of fluorine generally has a profound effect on the phys. and/or biol. properties of the target mol., we synthesized a series of fluorinated analogs of the previously reported compound 2 (I), some of which turned out to be remarkable PPARα and PPARγ dual agonists. Docking experiments were also carried out to gain insight into the interactions of the most active derivatives with both receptors. In the experiment, the researchers used many compounds, for example, Ethyl 2-hydroxy-3-phenylpropanoate (cas: 15399-05-0Category: esters-buliding-blocks).

Ethyl 2-hydroxy-3-phenylpropanoate (cas: 15399-05-0) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Category: esters-buliding-blocks

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

A One-Flask Synthesis of Weinreb Amides from Chiral and Achiral Carboxylic Acids Using the Deoxo-Fluor Fluorinating Reagent was written by Tunoori, Ashok Rao;White, Jonathan M.;Georg, Gunda I.. And the article was included in Organic Letters in 2000.Reference of 87694-53-9 This article mentions the following:

The reagent [bis(2-methoxyethyl)amino]sulfur trifluoride (Deoxo-Fluor reagent) converts carboxylic acids to the corresponding acid fluorides, which then react with N,O-dimethylhydroxylamine to give the corresponding Weinreb amides in high yields. The reaction proceeds without racemization when optically active acids are used as the starting material. This method is operationally simple and provides the products in high purity. Thus, N,N-diisopropylethylamine was added to a suspension of N,O-dimethylhydroxylamine hydrochloride in dichloromethane to give the free base N,O-dimethylhydroxylamine. Treatment of trans-crotonic acid with Deoxo-Fluor reagent resulted in the formation of the intermediate acid fluoride, which upon addition of N,O-dimethylhydroxylamine gave the desired N-methoxy-N-Me-trans-crotonamide [(2E)-N-methoxy-N-methyl-2-butenamide]. Similar treatment of N-BOC-L-alanine gave (-)-(S)-2-[(tert-butoxycarbonyl)amino]-N-methoxy-N-methylpropanamide. In the experiment, the researchers used many compounds, for example, (S)-tert-Butyl (1-(methoxy(methyl)amino)-1-oxo-3-phenylpropan-2-yl)carbamate (cas: 87694-53-9Reference of 87694-53-9).

(S)-tert-Butyl (1-(methoxy(methyl)amino)-1-oxo-3-phenylpropan-2-yl)carbamate (cas: 87694-53-9) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Reference of 87694-53-9

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Production of 12-hydroxy dodecanoic acid methyl ester using a signal peptide sequence-optimized transporter AlkL and a novel monooxygenase was written by Yoo, Hee-Wang;Kim, Joonwon;Patil, Mahesh D.;Park, Beom Gi;Joo, Sung-yeon;Yun, Hyungdon;Kim, Byung-Gee. And the article was included in Bioresource Technology in 2019.Name: 12-Methoxy-12-oxododecanoic acid This article mentions the following:

In this study, a signal peptide of AlkL was replaced with other signal peptides to improve the soluble expression and thereby facilitate the transport of dodecanoic acid Me ester (DAME) substrate into the E. coli. Consequently, AlkL with signal peptide FadL (AlkL_f) showed higher transport activity toward DAME. Furthermore, the promoter optimization for the efficient heterologous expression of the transporter AlkL_f and alkane monooxygenase (AlkBGT) system was conducted and resulted in increased ω-oxygenation activity of AlkBGT system. Moreover, bioinformatic studies led to the identification of novel monooxygenase from Pseudomonas pelagia (Pel), which exhibited 20% higher activity towards DAME as substrate compared to AlkB. Finally, the construction of a chimeric transporter and the expression of newly identified monooxygenaseenabled the production of 44.8 ± 7.5 mM of 12-hydroxy dodecanoic acid Me ester (HADME) and 31.8 ± 1.7 mM of dodecanedioic acid monomethyl ester (DDAME) in a two-phase reaction system. In the experiment, the researchers used many compounds, for example, 12-Methoxy-12-oxododecanoic acid (cas: 3903-40-0Name: 12-Methoxy-12-oxododecanoic acid).

12-Methoxy-12-oxododecanoic acid (cas: 3903-40-0) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Name: 12-Methoxy-12-oxododecanoic acid

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Effect of different drying technologies on the characteristics and quality of lemon slices was written by Xu, Qinglian;Pan, Hongjie;Shui, Yuru;Xing, Yage;Wu, Lin;Zheng, Faying;Fan, Xiangfeng;Bi, Xiufang. And the article was included in Journal of Food Science in 2022.Recommanded Product: (E)-3,7-Dimethylocta-2,6-dien-1-yl acetate This article mentions the following:

This experiment aimed to investigate the effects of four drying methods, namely, hot air drying (HAD), microwave drying (MD), vacuum drying (VD), and microwave vacuum drying (MVD), on the quality of lemon slices. The relevant indicators, including total phenolic content, ascorbic acid content, browning, color, reducing sugar content, volatile component measurements, and principal component anal. of 0 and 30 days storage, were compared after exposure to the four drying methods. The shortest time of 64 min was used to treat the lemon slices via MVD at 1 KW. These samples displayed the least damage after drying and the highest rehydration ratio of 4.12. The contents of VC, reducing sugars, and total phenols of MVD samples were significantly higher than those in the HAD, VD, and MD groups, retaining 105.94 mg/100 g, 21.35 g/100 g, and 77.81 mg GAE/g, resp., while their color difference values were also the smallest, with a browning degree of 3.55, significantly lower than those in the other treatment groups (p < 0.05), and the degree of browning of the samples in the HAD treatment group was the most serious; in terms of volatile flavor substances, the lemon slice samples in the MVD and HAD treatment groups were more diverse and of better quality. The order of product sensory evaluation was: MVD > VD > HAD > MD. The final scores after comprehensive anal. revealed the order of the four drying methods as MVD, HAD, VD, and MD. Therefore, MVD had a better effect on the sensory perception and nutritional properties of the lemon slices, providing a useful alternative to the conventional drying method. Practical Application : Lemon slices during drying are affected by various aspects, leading to changes in its color, aroma substances, and nutrient composition The results of this work will not only provide a tech. reference for the future production of high-quality dried lemon slices, but also have important implications for fresh-cut lemons in processing and storage. It also generates important implications for fresh-cut lemons in processing and storage. In the experiment, the researchers used many compounds, for example, (E)-3,7-Dimethylocta-2,6-dien-1-yl acetate (cas: 105-87-3Recommanded Product: (E)-3,7-Dimethylocta-2,6-dien-1-yl acetate).

(E)-3,7-Dimethylocta-2,6-dien-1-yl acetate (cas: 105-87-3) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Recommanded Product: (E)-3,7-Dimethylocta-2,6-dien-1-yl acetate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Mild halogenation of stabilized ester enolates by cupric halides was written by Shi, Xiaoxin;Dai, Lixin. And the article was included in Journal of Organic Chemistry in 1993.Recommanded Product: Diethyl 2-(prop-2-yn-1-yl)malonate This article mentions the following:

The reactions of various stabilized ester enolates of 2-keto, 2-(alkoxycarbonyl), 2-phosphoryl, and 2-(benzenesulfonyl) esters with cupric chloride or cupric bromide have been examined The reactions lead to 2-halo esters in good to excellent yields under mild conditions. Enolates which contain an unsaturated functionality such as a double bond, a triple bond, or an allylic or a benzylic moiety react with high chemoselectivity. In the experiment, the researchers used many compounds, for example, Diethyl 2-(prop-2-yn-1-yl)malonate (cas: 17920-23-9Recommanded Product: Diethyl 2-(prop-2-yn-1-yl)malonate).

Diethyl 2-(prop-2-yn-1-yl)malonate (cas: 17920-23-9) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Recommanded Product: Diethyl 2-(prop-2-yn-1-yl)malonate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics