One-Pot Synthesis of Imidazole-4-Carboxylates by Microwave-Assisted 1,5-Electrocyclization of Azavinyl Azomethine Ylides was written by Preti, Lisa;Attanasi, Orazio A.;Caselli, Emilia;Favi, Gianfranco;Ori, Claudia;Davoli, Paolo;Felluga, Fulvia;Prati, Fabio. And the article was included in European Journal of Organic Chemistry in 2010.Safety of Methyl 2-thienylacetate This article mentions the following:
Diversely functionalized imidazole-4-carboxylates, e.g., I, were synthesized by microwave-assisted 1,5-electrocyclization of 1,2-diaza-1,3-diene-derived azavinyl azomethine ylides. 1,2-Diaza-1,3-dienes were treated with primary aliphatic or aromatic amines and subjected to microwave irradiation in the presence of aldehydes. 3-Alkyl- and 3-arylimidazole-4-carboxylates were prepared in good yields through a one-pot multicomponent procedure. Modulation of the substituents at C-2, N-3, and C-5 was possible, and 2-unsubstituted imidazoles were obtained when paraformaldehyde was used. In the experiment, the researchers used many compounds, for example, Methyl 2-thienylacetate (cas: 19432-68-9Safety of Methyl 2-thienylacetate).
Methyl 2-thienylacetate (cas: 19432-68-9) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Safety of Methyl 2-thienylacetate
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics