Wang, Wanyi published the artcileAnalysis, occurrence, toxicity and environmental health risks of synthetic phenolic antioxidants: A review, Recommanded Product: Propyl 3,4,5-trihydroxybenzoate, the publication is Environmental Research (2021), 111531, database is CAplus and MEDLINE.
A review. The continuous improvement of living standards is related to higher requirements for the freshness and taste of food. For example, synthetic phenolic antioxidants (SPAs) are added to fats and fried foods as food additives to minimize the oxidative rancidity of oils and fats. Hence, the global use of SPAs is increasing year by year. Di-Bu hydroxytoluene is one of the widely used SPAs, often in combination with Bu hydroxyanisole or gallate SPAs. The extensive use of these compounds makes them and their transformation products to be widespread in various environmental matrixes, including indoor dust, wastewater, river water, sewage sludge, and sediment, as well as human samples, such as nails and urine, at concentrations varying from nanogram per g (ng/g) to microgram per g (μg/g). Animal experiments have shown that high-dose SPA exposure is toxic, which may lead to DNA damage and mismatches and the development of cancerous tumors. Since the biosphere shares the same set of genetic codes, humans and animals have many identical or similar feedback mechanisms and information pathways. Therefore, the damage of SPAs to animals may also threaten human health. This review discusses the properties, occurrence, anal., and environmental health risks of typical SPAs, including Bu hydroxyanisole, di-Bu hydroxytoluene, tert-butylhydroquinone, Pr gallate, octyl gallate, and lauryl gallate, used as food additives. In addition, AO2246, which is used in food packaging bags, is also considered. Future research directions on SPAs and their transformation products (TPs) are identified and discussed.
Environmental Research published new progress about 121-79-9. 121-79-9 belongs to esters-buliding-blocks, auxiliary class Natural product, name is Propyl 3,4,5-trihydroxybenzoate, and the molecular formula is C24H12, Recommanded Product: Propyl 3,4,5-trihydroxybenzoate.
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