Lee, Koo published the artcileReaction of diethyl phosphorochloridite with enolates: a general method for synthesis of β-keto phosphonates and α-phosphono esters through carbon-phosphorus bond formation, Application In Synthesis of 5340-78-3, the publication is Journal of Organic Chemistry (1991), 56(19), 5556-60, database is CAplus.
The reaction of ketone enolates, e.g., from cyclopentanone and LDA, with di-Et phosphorochloridite, followed by air oxidation of the immediate reaction products, has proven to be a general and convenient method for preparation of β-keto phosphonates, e.g., I. Fourteen β-keto phosphonates were prepared by this method, in an average yield greater than 60%. This procedure also appears to be applicable to the preparation of both α-phosphono aldehydes and α-phosphono esters. Although special precautions may be necessary to avoid aldol condensation during formation of aldehydes enolates, in two cases the resulting enolates reacted readily with di-Et chlorophosphite. Finally, a set of five Et esters was converted to α-phosphono esters by this method. Yields of the α-phosphono esters are influenced by steric hindrance at the enolate carbon, but the average yield for this series was ca. 70%. Because this synthetic method relies upon an electrophilic phosphorus reagent for formation of the C-P bond, it is complementary to the traditional Arbuzov synthesis.
Journal of Organic Chemistry published new progress about 5340-78-3. 5340-78-3 belongs to esters-buliding-blocks, auxiliary class Aliphatic Chain, name is Ethyltert-butylacetate, and the molecular formula is C8H16O2, Application In Synthesis of 5340-78-3.
Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics