Yadav, Suresh Kumar published the artcileCobalt(III)-Catalyzed Regioselective [4 + 2]-Annulation of N-Chlorobenzamides with Substituted Alkenes, Application In Synthesis of 583-04-0, the main research area is dihydroisoquinolinone regioselective preparation; chlorobenzamide allylic compound annulation cobalt catalyst.
Synthesis of 3,4-dihydroisoquinolinone derivatives I [R1 = H, 6-Me, 7-Cl, etc.; R2 = S(O)2Ph, OPh, CN, etc.] via Co(III)-catalyzed redox-neutral [4 + 2] annulation of N-chlorobenzamides/acrylamides with substituted alkenes at ambient temperature in good yields was demonstrated. Intriguingly, the synthetically useful functional group of allylic coupling partners such as sulfonyl, carbonate, acetate, phosphate, amide, nitrile, and silane were retained in the final cyclized product. The present annulation reaction was compatible with various substituted benzamides and allylic coupling partners. To support the proposed reaction mechanism, competition experiments, deuterium labeling studies, and kinetic isotope effect studies were performed.
Journal of Organic Chemistry published new progress about Allylic compounds Role: RCT (Reactant), RACT (Reactant or Reagent). 583-04-0 belongs to class esters-buliding-blocks, name is Allyl benzoate, and the molecular formula is C10H10O2, Application In Synthesis of 583-04-0.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics