Pollack, Scott R.’s team published research in Journal of Organic Chemistry in 2021-09-03 | CAS: 120157-98-4

Journal of Organic Chemistry published new progress about Amino esters Role: SPN (Synthetic Preparation), PREP (Preparation). 120157-98-4 belongs to class esters-buliding-blocks, name is tert-Butyl acetylcarbamate, and the molecular formula is C7H13NO3, Formula: C7H13NO3.

Pollack, Scott R. published the artcileMetal-free stereoselective synthesis of (E)- and (Z)-N-monosubstituted β-aminoacrylates via condensation reactions of carbamates, Formula: C7H13NO3, the main research area is carbamate alkoxyacrylate acid catalyst metal free diastereoselective condensation reaction; dialkoxypropanoate carbamate acid catalyst metal free diastereoselective condensation reaction; propynoate carbamate base catalyst diastereoselective condensation reaction; aminoacrylate preparation stereoselective metal free.

Two efficient, stereoselective methods for the preparation of (E)- or (Z)-β-aminoacrylates via acid- or base-promoted condensation reactions of carbamates are described. The base-promoted reaction is E-selective, while acid catalysis can, through the choice of solvent, selectively form E or Z. The acid-catalyzed E-selective process proceeds through a crystallization obviating the need for chromatog. purification

Journal of Organic Chemistry published new progress about Amino esters Role: SPN (Synthetic Preparation), PREP (Preparation). 120157-98-4 belongs to class esters-buliding-blocks, name is tert-Butyl acetylcarbamate, and the molecular formula is C7H13NO3, Formula: C7H13NO3.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics