Tkachuk, Volodymyr V. published the artcile2-Carbamimidoylbenzoic Acid as a New Effective and Available Precursor for the Synthesis of Substituted 2-(Pyrimidin-2-yl)-benzoic Acids, COA of Formula: C6H10O3, the publication is Synthesis (2021), 53(2), 371-382, database is CAplus.
A new approach to the synthesis of 2-(pyrimidin-2-yl)benzoic acids I (R = Me, Et, Ph, OH, NH2) based on the ring contraction of the 2-carbamimidoylbenzoic acid with 1,3-dicarbonyl compounds R1CH2C(O)OR2 (R1 = C(O)Me, C(O)Et, C(O)Ph, C(O)OEt, CN; R2 = Me, Et), and their synthetic equivalent has been developed. The intramol. condensation of the obtained acids with 1,3-dielectrophiles proceeds with the formation of the 4,6-dihydropyrimido[2,1-a]isoindole-4,6-diones II (R = Me, Et, Ph, NH2), the pyrrolidone ring of which is easily opened under the action of weak nucleophiles. The reaction of 2-carbamimidoylbenzoic acid with chromones III (R3 = H, CF3; R4 = 4-chlorophenyl, 2-nitrophenyl), which have an aryloxy group at 3-position does not stop at the step of pyrimidine ring formation and undergoes further spontaneous cyclization into 2-(benzo[4,5]furo[3,2-d]pyrimidin-2-yl)benzoic acids IV.
Synthesis published new progress about 30414-53-0. 30414-53-0 belongs to esters-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Ketone,Ester, name is Methyl 3-oxovalerate, and the molecular formula is C18H10F3NO3S2, COA of Formula: C6H10O3.
Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics